Fig. 3

iNSCs transplantation improves cognitive deficits in AD mice. A In the place navigation testing of MWM training, AN mice exhibited significantly shorter escape latencies vs. AD mice and AP mice (B). In the spatial probe test, AN mice spent a significantly longer time in the target quadrant than AD and AP (n = 10, p < 0.001) and performed similarly to WT mice (n = 10, p > 0.05) as determined by one-way ANOVA. C AN mice crossed the platform significantly more than AD and AP mice (n = 10, p < 0.05) and performed similarly to WT mice (n = 10, p > 0.05)