Fig. 4
The role of NO signaling in endothelium-dependent vasorelaxation (a, b) and adrenergic contraction (c, d) of isolated thoracic aorta in female Wistar and HTG rats. W Wistar female rats, HTG hereditary hypertriglyceridemic female rats, A- perivascular adipose tissue denuded rings, A + perivascular adipose tissue preserved rings, LN– rings without incubation with NOS inhibitor (NG-nitro-L-arginin methyl ester), LN+ rings incubated with NOS inhibitor (NG- nitro-L-arginin methyl ester). The results are presented as the mean ± S.E.M., and differences between groups were analyzed by three-way ANOVA. a, c: ***p < 0.001 vs W A– LN–, +++p < 0.001 vs HTG A– LN–, ###p < 0.001 vs W A– LN + ; b, d: ***p < 0.001 vs W A + LN–, +++p < 0.001 vs HTG A + LN–, #p < 0.05 vs W A + LN +