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Table 1 Biometrical and lipid parameters in Wistar and HTG rats

From: Female prediabetic rats are protected from vascular dysfunction: the role of nitroso and sulfide signaling

 

Bonfferoni post hoc test

Two-way ANOVA

Parameters

Wm

HTGm

Wf

HTGf

Sex

Strain

n

8

9

8

8

  

BW (g)

424.5±10.77

413.7±8.69

289.5±3.88+++ 

250.5±3.05**+++ 

F (1, 31) = 398.89;

p = 1.7 × 10–18

F (1, 31) = 11.14; p = 0.002

HW (g)

1.24±0.03

1.06±0.02***

0.86±0.02+++ 

0.79±0.01+++

F (1, 31) = 233.47;

p = 2.08 × 10 −5

F (1, 31) = 34.02;

p = 2.53 × 10–6

Chol (mmol/L)

1.74±0.11

1.61±0.06

2.03±0.13

1.67±0.10

F (1, 33) = 3.09; p = 0.09

F (1, 33) = 6.44; p = 0.02

HDL-C (mmol/L)

1.27±0.08

0.87±0.02***

1.17±0.08

0.69±0.04***

F (1, 30) = 4.99; p = 0.03

F (1, 30) = 50.46;

p = 9.96 × 10–8

TAG (mmol/L)

1.57±0.12

5.26±0.42***

1.58±0.04

5.90±0.16***

F (1, 39) = 176.54; p = 0.29

F (1, 39) = 1.13;

p = 1.18 × 10–15

  1. The results are presented as the mean ± S.E.M., and differences between groups were analyzed by two-way ANOVA. ** p < 0.01, ***p < 0.001 vs. W within the respective sex, +++p < 0.01 vs. m within the respective strain
  2. BW body weight, HW heart weight, HW/BW ratio of heart weight to body weight, OGTT AUC the area under the glycemic curve during the oral glucose tolerance test, Chol total cholesterol, HDL-C high-density lipoprotein cholesterol, TAG triacylglycerols, n number of rats, Wm Wistar male rats, HTGm hereditary hypertriglyceridemic male rats, Wf Wistar female rats, HTGf hereditary hypertriglyceridemic female rats