Fig. 5
From: Ptprd deficiency promotes tau hyperphosphorylation and impairs cognitive function in aged mice
Loss of Ptprd reduces PSD95 levels in the brain cortex of older mice. Western blot analysis of cortical (A) and hippocampal lysates (C) from 18-month-old Ptprd WT and Ptprd KO mice probed for PSD95. The same lysates were also analyzed for HSP90 as loading control. Quantification of the relative levels of PSD95 was assessed by densitometry of cortical (B) and hippocampal western blots (D).*p < 0.05; n = 12–15