Fig. 5
From: NAMPT regulates mitochondria and oxidative stress level for mouse early embryo development
Loss of NAMPT activity induces early apoptosis in mouse embryos. (A) Typical images for the 2-cell embryo staining with Annnexin-V after 50 µM dose of FK866 treatment. Green, Annexin-V; blue, DNA. Bar = 20 μm. (B) The percentage of Annexin-V positive embryos increased in the FK866 treatment groups compared with the control. *, P < 0.05. (C) The mRNA level of apoptotic gene after FK866 treatment, which these genes showed altered expression level after inhibition of NAMPT activity. *, P < 0.05