Fig. 1

Deleting exon 17 of Kit impairs mouse testicular development. (A) Size of mouse testes, epididymes and seminal vesicles. (B) Individual weights of the mice. (C) The ratio of mouse testis weight to body weight. (D) The ratio of mouse epididymis weight to body weight. (E) The ratio of mouse seminal vesicle weight to body weight. n = 3, Student’s t test; **P < 0.01, *P < 0.05. (F) H&E staining of testis sections from 5-, 7- and 9-week-old mice. Scale bar = 50 μm (scale bar in magnified image = 30 μm). (G) Lumen vacuolization ratio. (H) Thickness of the seminiferous tubules. (I) Diameter of the seminiferous tubules. The data are presented as the mean ± SEM of three Kit ^D17/+ and Kit ^+/+ males, with 50 seminiferous tubule cross-sections analyzed per individual. Student’s t test; ^**P < 0.01, ^*P < 0.05